As. Pac. J. Mol. Biol. & Biotech., Apr 2013 Vol. 2, 37-42
Review The Cytochrome P450s
Fatma M.A. El-garj*, Mustafa F.F. Wajidi
School of Distance Education, Universiti Sains Malaysia, 11800 Penang, Malaysia.
* Author for correspondence: Fatma M.A. El-garj
School of Distance Education, Universiti Sains Malaysia, 11800 Penang, Malaysia.
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Abstract.
Cytochrome P450 monooxygenases are versatile biocatalysts that incorporate oxygen into an enormous range of molecules. The cytochrome P450 proteins are involved in the catalysis of different reactions and these properties have been used for drug improvement. The protein family also includes compounds producing properties such as resistance to insecticides, and the synthesis of valuable chemicals. In this review, we will discuss various aspects of the structure and function of the cytochrome P450s.
